Methyl CpG

Ortho Molecular Products

Methyl CpG

Supports optimal methylation and cardiovascular health. Supports healthy homocysteine levels. Increases neurotransmitter production.

Supplement Facts

Regular price $38.40

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Benefits at a Glance

Supports optimal methylation and cardiovascular health

Supports healthy homocysteine levels

Increases neurotransmitter production

Supports primary detoxification pathways

Promotes DNA repair

Methyl CpG is a comprehensive formula that includes targeted amounts of five key nutrients designed to support methylation and homocysteine balance in the body

Staying Healthy ▶ Supplement Facts ▶
Methylation is a vitamin-requiring biochemical process in the body that is critical for supporting many aspects of mental and physical health including regulating gene expression. Methylation occurs billions of times every second and helps the body to repair DNA on a continual basis. However, when methylation processes in the body slow down, an increase in the breakage of DNA strands can occur. In addition to maintaining DNA repair, methylation reactions help maintain optimal neurotransmitter production, homocysteine balance for cardiovascular health, and the recycling of molecules that are required for detoxification and healthy inflammatory response. Methylation is also required for proper energy metabolism, immune and nerve cell function. Proper methylation can be inhibited by nutrient deficiencies including folate, and B2, B6 and B12. Certain medications such as acetaminophen, aspirin, ibuprofen and oral contraceptives can also deplete blood levels of these crucial B vitamins. Methyl CpG is a comprehensive formula that includes targeted amounts of five key nutrients designed to aggressively support methylation and homocysteine balance in the body. Methyl CpG provides high-concentration folate as Quatrefolic® - 100% 5-MTHF, the biologically active form, and trimethyl glycine. The formula includes key methylation vitamins B2, B6 and B12 (methylcobalamin). This specific blend of methyl donors promotes DNA repair, homocysteine balance, neurotransmitter production, hormone balance and optimal detoxification.
This product is designed to support methylation and healthy homocysteine levels. It contains 5-MTHF, the biologically active form of folate along with betaine, B2, B6, and B12. The Betaine is a methyl donor that has been shown to be beneficial in protecting against fatty liver. References: 1. Barak AJ, Beckenhauer HC, Matti J, Tuma DJ. Dietary betaine promotes generation of hepatic S-adenosylmethione and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res 1993;17:552-5.

Serving Size: 1 Capsule

Amount per serving

  • Riboflavin (Vitamin B2 USP) .... 25mg
  • Vitamin B6 (as Pyridoxine Hydrochloride USP) .... 50mg
  • Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid glucosamine salt) .... 2,000mcg
  • Vitamin B12 (as Methylcobalamin) .... 1,000mcg
  • Betaine (Trimethylglycine) .... 500mg
  • Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid, Calcium Silicate, and Silicon Dioxide.

Dosage and use

  • 1 capsule per day or as recommended by your health care professional

Manufacturer's Description


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DISCLAIMER: Statements made are for educational purposes and have not been evaluated by the US Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. If you have a medical condition or disease, please talk to your doctor prior to using the recommendations given.