Cardiovascular disease (CVD) remains the second leading cause of death in North America. Metabolic syndrome (MetS) is a risk factor for CVD and renal damage. This comprehensive test evaluates risk for CVD plus too often associated MetS. Many of the risk factors and metabolic abnormalities associated with both CVD and MetS are lifestyle-related. Objective advanced laboratory assessment of glucose, lipid, and lipoprotein metabolism abnormalities reveals important information in determining lifestyle, dietary, and therapeutic approaches.