Increased oxidative stress can occur when exposed to environmental contaminants, including heavy metals (lead, mercury, cadmium, arsenic, iron and others), pesticides, radiation, industrial chemicals including paints, household cleaners, plastics (BPA, PCBs) and phthalates.1 Toxic overload increases demands on the immune system, thyroid and adrenal glands, leading to metabolic imbalances including:
Insulin resistance and insulin signaling problems; type 2 diabetes
Thyroid and sex hormone imbalances
Neurodegenerative conditions, including Parkinson’s and Alzheimer’s disease
Chronic inflammatory signaling
Attention deficit-hyperactivity disorder (ADHD)
Environmental intoxicants can act as endocrine disruptors, interfering with the endocrine system and produce adverse developmental, reproductive, neurological, and immune effects in both humans and wildlife. A wide range of substances, both natural and man-made, are thought to cause endocrine disruption, including pharmaceuticals, dioxin, and dioxin-like compounds, polychlorinated biphenyls, DDT and other pesticides, and plasticizers such as phthalates and bisphenol A (BPA).5 Pesticide intoxication can lead to metabolic imbalances such as insulin resistance and low thyroid function.6 The plasticizer BPA is also known to increase the risks of insulin resistance.
Low testosterone levels have been linked to excess belly fat and insulin resistance, and phthalates have been reported to interfere with or block testosterone function. Phthalates are commonly found in cosmetics and personal care items such as shampoos, and a recent study reported that approximately 75% of the United States population has measurable levels of phthalates in their bodies.
Heavy metals, including lead, mercury, arsenic, and cadmium, are environmental toxicants known to impact numerous physiological systems, including the reproductive, hepatic, renal, and nuero-endocrine immune-systems. Chronic heavy metal exposure may lead to the up-regulation of inflammatory signaling pathways. Mercury, commonly found in dental amalgam fillings, can cause microglia activation and lead to localized flora disturbances and immune activation in the gut. This may increase inflammatory signaling and nuero-endocrine-immune imbalances, leading to neurodegenerative diseases like Alzheimer’s disease. Similarly, chronic lead exposure can damage the neuro-endocrine-immune system, leading to inflammatory signaling.
Some of these contaminants are also found in our food supply, including pesticides on fruits and vegetables, mercury in fish and high fructose corn syrup, BPA in the lining of cans and plastic bottles, and chemicals used to preserve, flavor and color foods. Also, quite a few Chinese dietary supplements have been reported contaminated with heavy metals and other impurities, so prudence when using these supplements is advised.
Benefits at a Glance
Helps detoxify heavy metals and other environmental contaminants
Heavy metal chelator
Helps detoxify organic compounds including pesticides
Amount per serving:
Dosage and use
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DISCLAIMER: Statements made are for educational purposes and have not been evaluated by the US Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. If you have a medical condition or disease, please talk to your doctor prior to using the recommendations given.