Ortho Molecular Products

Saccharomyces boulardii

Saccharomyces boulardii is a probiotic used in the treatment of diarrhea, IBS, IBD, and Candida overgrowth. Although S. boulardii is a yeast itself, studies have shown it to reduce the levels of C. albicans in the body, by up to 90%.

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S. boulardii was first identified in the 1920s by French microbiologist Henri Boulard. Since its discovery, there have been 250 peer-reviewed articles examining S. boulardii, making this one of the most studied probiotics available. S. boulardii is a non-pathogenic yeast and maintains distinct taxonomic and physiological differences from Saccharomyces cerevisiae or “brewer’s yeast.”[1,2] S. boulardii has been shown to support gastrointestinal health by boosting secretory IgA (sIgA) levels. sIgA is an immunoglobulin (protective antibody) that is found in the digestive tract and in mucosal secretions throughout the body. Maintaining healthy sIgA levels is crucial for supporting immune health, particularly in the GI system where there can be significant exposure to pathogenic organisms and viruses. sIgA acts as the first line of defense against foreign invaders in the gut by attaching and neutralizing proteins that are unrecognized by the body. Depleted levels of sIgA are often found in people with low immune response, food intolerance and dysbiosis. Dysbiosis occurs when fewer than normal probiotic organisms and an overabundance of potentially harmful bacteria, yeast or parasitic organisms prevail. In addition to boosting sIgA levels, S. boulardii promotes GI health by competing for space and nutrients against pathogens.

In 53 clinical trials, encompassing 8,475 subjects investigating the safety and efficacy of S. boulardii in pediatric and adult populations, 43 trials (81%) found significant protective efficacy of this probiotic.  Supplementation with S. boulardii is an important part of supporting GI health and strengthening the immune system, particularly for those with recent antibiotic use. Each capsule of Saccharomyces boulardii includes 5 billion CFUs of this health-promoting, probiotic yeast.

Benefits at a Glance

Balances Gastrointestinal Flora

Boosts Immune Function

Supports Gastrointestinal Barrier Function and Integrity

Manufacturer's Description

Saccharomyces boulardii is a health-promoting, probiotic yeast. To be an effective probiotic, microorganisms must have certain qualities to withstand the natural defense factors of the host. These include resistance to gastrointestinal (GI) transit and the ability to thrive at human core temperatures. Saccharomyces boulardii is a stomach acid-resistant probiotic, proven to survive high temperatures and transit into the intestines. As a probiotic, S. boulardii actively promotes healthy gastrointestinal flora, strengthens intestinal barrier function, and enhances immune function. This formulation of Saccharomyces boulardii is freeze-dried, lactose-free, and strain-verified through genetic typing to ensure
maximum efficacy.

Supplement Facts

Serving Size: 1 capsule

Amount per serving:

Saccharomyces boulardii 5 billion CFU

Other ingredients:

Does Not Contain:  Wheat, gluten, soy, corn, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners or preservatives.

Cautions:  If you are pregnant or nursing, consult your physician before taking this product.


Dosage and use

Take 1 capsule two times per day or as recommended by your health care professional.


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DISCLAIMER: Statements made are for educational purposes and have not been evaluated by the US Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. If you have a medical condition or disease, please talk to your doctor prior to using the recommendations given.